For US Audiences Only
For US Audiences Only

WHAT IS CYSTADROPS?

CYSTADROPS (sys-tah-drops) is a prescription eye drop that reduces cystine crystals in the cornea with practical, 4 times a day dosing.

CYSTADROPS was approved by the Food and Drug Administration based on studies that demonstrated safety and effectiveness in people with cystinosis.

One study showed a 12% decrease in cystine crystals in the cornea after 30 days of treatment and a 40% decrease in cystine crystals in the cornea after 90 days.

A longer-term study showed a 30% decrease in cystine crystals in the cornea that was maintained for 5 years.

HOW DOES CYSTADROPS WORK?

The active ingredient in CYSTADROPS, cysteamine, enters the lysosomes of cells in the cornea. Once inside, it breaks apart cystine, which can then be transported out of the lysosomes. As a result, the build-up of corneal cystine crystals decreases over time with continuous treatment.

CYSTADROPS is a viscous formulation that appears as a thick liquid solution applied directly to the eye in order to reach the cells in the cornea.

WHAT ARE POSSIBLE SIDE EFFECTS OF CYSTADROPS?

  • The most common side effects are eye pain (stinging), blurred vision, eye irritation (burning), eye redness, discomfort at instillation site (sticky eyes or sticky eyelids), eye itching, watery eyes, medicine deposit on the eye lashes or around the eyes.

Talk to your doctor if you are experiencing any side effects due to treatment.

HOW LONG DO PATIENTS TAKE CYSTADROPS?

Ongoing, continuous use of cystine-depleting eyedrops may reduce the build-up of cystine crystals in the cornea. As shown in the studies, corneal cystine crystals were reduced over time when CYSTADROPS was used continuously.

INDICATIONS AND IMPORTANT SAFETY INFORMATION

Important Safety Information

  • To minimize the risk of contamination, do not touch the dropper tip to any surface. Keep bottle tightly closed when not in use.